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Rimonabant is not yet accustomed for use in the United States, area it is accepted as Zimulti. 15 -- People who take the weight-loss drug rimonabant may face heightened risks for severe depression and anxiety, Danish researchers report. "If one is using rimonabant, patients should be monitored carefully for the emergence of depressive symptoms and/or suicidal thoughts," he added. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee did not recommend approval of Zimulti (rimonabant) to the US FDA for use in obese and overweight patients with associated risks factors because of continuing concerns about increased risks for suicidal thoughts among some users.
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